• Foundation Skincare Night Renewal 2% Granactive Retinoid
  • A woman using 2% Granactive Retinoid to help with the appearance of fine lines and wrinkles
  • Night Renewal 2% Granactive Retinoid Ingredients
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  • Dermatologist Formulated
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Dermatologist Formulated

Night Renewal Cream

Night Renewal Cream

with 2% Granactive Retinoid

$45
$45
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If you decide to return a product for any reason, please contact us. We offer a money back guarantee on your first purchase of each item from our line, within 30 days of the purchase date. The UnTangled Hair Supplement and Hair Serum have a 60 days refund period from the purchase date. For subsequent purchases of the same product, refunds are only applicable in cases of defects or damage. If you have purchased multiple units of the same product in your initial order, only one unit is eligible for a refund.

Hydrate and restore your skin with Night Renewal Cream. This next-level formulation combines 2% Granactive Retinoid with essential peptide growth factors and plant-based botanicals to visible reduce the appearance of fine lines, wrinkles, dark spots and sagging skin. It works on multiple levels to offer all of the skin-renewing benefits of prescription retinoic acid, with less irritation.

Why it’s Different

  • Dermatologist + chemist formulated
  • Engineered with 2% Granactive Retinoid to rejuvenate with less irritation
  • Combines Matrixyl Synthe'6 peptide serum for powerful anti-aging benefits
  • Uses peptide growth factors to increase collagen and elastin
  • Contains superior antioxidant properties thanks to plant-based botanicals

Key Benefits

  • Encourages collagen synthesis to preserve skin firmness and elasticity
  • Retinoid advantages gentle enough for sensitive skin
  • Accelerates cellular turnover to help renew skin
  • Hydrates to keep skin clear, smooth and minimize problems
  • Brightens the appearance of dark spots and uneven skin
  • Anti-inflammatory benefits help control rosacea and acne-prone skin
  • Visibly improves the look of fine lines, wrinkles and skin texture

How to use

  • Apply one pump to cleansed skin in the evening.
  • Massage gently all over your face, avoiding the eye area.
  • Night Renewal Cream may be used nightly but if you experience irritation, limit use to three nights per week then build up slowly as your skin acclimates.
  • Follow with moisturizer if required. To minimize irritation, we recommend pairing with Hyaluronic Acid Lotion.

Recommended Routine

Each Evening

  • Cleanse and apply Niacinamide Lotion 10%: calms skin and contributes to DNA repair.
  • Moisturize with Night Renewal Cream: boosts collagen, accelerates cell regeneration and increases moisture to improve your skin’s barrier function.
  • Hydrate with Hyaluronic Acid Lotion: draws water to the surface to boost hydration and moisturize your skin.

What it Helps

  • Aging skin: retinoids are clinically proven to improve the appearance of fine lines, wrinkles and thin or sagging skin
  • Uneven Skin Tone: decreases the effects of UV induced skin damage to help fade mild to moderate dark spots
  • Poor Skin Texture: works at a cellular level to unblock pores and create smoother skin
  • Acne: minimizes inflammation and encourages healthy pores to reduce the frequency of breakouts

What to Expect

Getting Started:
Apply Night Renewal Cream every evening after cleansing and toning, but before moisturizing. Mild peeling during the first two or three weeks is normal, but if you experience discomfort or irritation, reduce usage to every other night then build back to nightly.

After 30 Days:
Your skin should tolerate the retinoid really well after a month’s use. Any minor peeling should have slowed down or completely stopped. Oily skin types may also start to notice a reduction in sebum, especially around the T-zone.

After 90 Days:
From now on, you should experience nothing but good results. Benefits include less noticeable pores, softer fine lines and wrinkles, firmer-looking skin and a more even, refined skin texture and tone. But remember: don’t stop now as these incredible effects will continue with consistent use.

Dermatologist Do’s and Don’ts


The Do’s

  • Use nightly for the most visible results.
  • Limit sun exposure and apply a broad-spectrum, mineral-based sunscreen every morning to protect your skin from UV damage. We recommend a minimum of SPF 30, preferably SPF 50.
  • Combine with Neck Firming Cream and Hyaluronic Acid for further anti-aging benefits.
  • Be patient. Expect to see true results from three months onwards.
  • Depending on your skin type, begin using as early as adolescence.
The Don’ts

  • Avoid combining with other retinoid treatments. This is unnecessary and may irritate your skin.
  • If using acne medications, check with your physician first.
  • Avoid the eye area. If direct contact occurs, rinse thoroughly with water.
  • Don’t apply Night Renewal Cream after moisturizing. It should be applied after cleansing and toning, but before moisturizing.
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What is Granactive Retinoid?

  • A high-performance retinoic acid that delivers all the benefits of Vitamin A with fewer side effects like redness and peeling.
  • Gentle enough for all skin types (even for those with sensitive skin) and easily incorporated into your daily skincare routine.
  • Comparable in effectiveness to well-known prescription medications.
  • Clinically proven to help minimize skin damage, reduce acne breakouts and improve the visible signs of skin aging.

DR. ANTHONY NUARA, MD PHD FAAD

Our Granactive Retinoid & Matrixyl Synthe'6
combo has proven very tolerable and can significantly
improve fine lines, wrinkles and skin texture in just

90 DAYS

  • Moisturizing ingredients include aloe, shea butter and Vitamin E to help calm and soothe the skin.

  • Works with even the most sensitive skin to hydrate while delivering powerful anti-aging benefits.

  • No synthetic fragrances or harsh chemicals like sulfates, parabens, PEGS and phthalates.

What to expect from Night Renewal Cream

The First 30 Days

Apply each evening after cleansing and toning, but before moisturizing. Mild peeling during the first 2-3 weeks is normal, but if you experience discomfort or irritation, reduce usage to every other night then build back to nightly.

After 90 Days – Best Results Milestone!

Benefits include less noticeable pores, softer fine lines and wrinkles, firmer-looking skin and a more even, refined skin texture and tone. Effects will continue with consistent use.

Customer Reviews

Overall rating: 4.529412 / 5 from 17 reviews.

AI Generated Review Summary

Summary topics

Review topics: ["smell","skin","cream"].

Review highlights

Reviews

Yay! Quality skin care that works perfect for me!

"I was excited to receive my products and am quite happy with them. I look forward to my everyday quick routine. My aged skin feels so fresh, smooth & clean. Improvements to my skin are definitely noticeable."

— Jude (5/5)

Off the charts amazing

"This is the exact night cream that I needed to restore my youthful glow and fine lines. It's amazing. I use it every night diligently and it has transported my skin. I will buy it over and over again."

— Jill (5/5)

Night Renew cream

"I really like the night renew cream, it really makes a difference using this cream and I really appreciate Anthony Nuara MD, for recommendations. This product is amazing it help me with dark spots and I am happy about it"

— Yola S. (5/5)

Very Pleased with this serum

"Gentler on my skin than other retinol based products. Doesn’t irritate my very sensitive skin."

— Sandra B. (5/5)

Just what I needed

"I’m in my 50s and needed a retinol product that can help me with the age and sun spots I have as well as fine lines, and the Night Renewal Cream has been perfect. I’ve been using nightly for about a month and already seeing results, without any irritation or flaking. Love!"

— Maryam A. (5/5)

Azalaic Acid Cream Review

"The last jar of Azelaic Acid Cream I ordered was only half full of cream. This is an expensive product, given the 1 fl. ounce that is provided. Please ensure that there is a full amount in the jars so that your customers do not feel they are being deprived of the full amount. Otherwise, you will start seeing negative reviews of your products. They are high-quality but you need more stringent control measures in place."

— Justin R. (1/5)

A great product that provides

"A great product that provides results!"

— Lisa C. (5/5)

Remove the harsh preservative

"Please remove Phenoxyethanol and fragrance from this and it could be a really great product."

— Heather (1/5)

I use it everynight! I

"I use it everynight! I have better skin."

— cynthia a. (5/5)

"I’ve been using this product since 2019. This retinoid definitely hydrates and helps to restore your skin. Helping to keep my skin clearer, smoother and minimize problems."

— Bushana (5/5)

Q&A

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